Changes

[[Overtraining Syndrome]] has similarities with clinical depression<ref name="OTBrainMarathon"/> <ref name="OTDepression"/>]<ref name="OTMentalStigma"/>. There are several signs, symptoms, brain structures, newer transmitters, endocrine pathway dysfunctions, and immune system responses that are shared between [[Overtraining Syndrome]] and major depression<ref name="OTDepression"/><ref name="OTMentalStigma"/>. There are reports of successfully treating [[Overtraining Syndrome]] with [http://en.wikipedia.org/wiki/Noradrenergic_and_specific_serotonergic_antidepressant serotonergic antidepressants]<ref name="OTMentalStigma"/> and [http://en.wikipedia.org/wiki/Selective_serotonin_reuptake_inhibitor SSRI antidepressants] <ref name="OTDepression"/>. Alberto Salazar returned to competitive racing after 10 years of disabling [[Overtraining Syndrome]] after taking Prozac<ref name="OTDepression"/>. It could be argued that OTS and Major Depression are actually the same illness]<ref name="OTMentalStigma"/>. Exercise tends to protect against depression and other mental illnesses, but that does not give athletes complete immunity]<ref name="OTMentalStigma"/>. These benefits is somewhat undermined by the fact that athletes tend to be even more susceptible to undue diagnosis and inadequate treatment for depression and other mental illnesses]<ref name="OTMentalStigma"/>. Of course, due to the complexities of diagnosing [[Overtraining Syndrome]], the possibility that an athlete is suffering from clinical depression rather than [[Overtraining Syndrome]] must always be considered.