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From Fellrnr.com, Running tips
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The following are a list of possible approaches to treating a Morton's Neuroma.
* The most important approach is to avoid any footwear that squeezes the forefoot. This will aggravate the nerve, so avoid any shoe that puts any pressure on the sides of the forefoot. It may help to go up a shoe size, or cutting away the shoe where it touches the sides of the forefoot.
* Check for alternative causes. One runner found their pain was caused by calluses! * Toe stretches stretchers can help spread the metatarsal heads. I've used XXX [http://www.amazon.com/Telebrands-PC-PAMPEREDTOES-Deluxe-Pampered-Toes/dp/B002HMCIOK/ref=sr_1_1?ie=UTF8&qid=1295090906&sr=8-1&rps=1 Pampered Toes] and it seems to help.
* Many people find that a metatarsal pad in their shoes help relieve the problem. I know of runners who will not run without metatarsal pads.
* Orthotics may help, though I personally dislike orthotics and believe they are likely to cause other problems.