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* Research indicates that there is a very wide variability in the response to altitude (IHT or other) and tolerance of extreme hypoxia. Future research may provide methods of overcoming the lack of response in some individuals.
==Western Research==
* Research <ref name="jack"/> using highly trained runners showed no running improvement with IHT This research used simulated altitudes of 15,000 at the start rising to 20,000 feet at the end. This gave O2 saturations of 90% at the start, going down to 80% at the end. The athletes were given 5 mins hypoxic, 5 mins nomal for 70 minutes total for five days per week, 4 weeks total. Given the * A similar research from the USSR<ref name="junis"/> study showed a significant improvement in 3K running performance. This study used 90 minutes of IHT (5 hypoxic:5 normal) for 15 days over a three week period, using 13, it is possible that 000 feet at the 7x 5 minutes exposure is insufficient start to gain 19,000 feet at the required benefitsend.
* A study<ref name="EPO"/> looking at Hypoxia EPO, a hormone that stimulates red blood cell production showed a ~50% increase in EPO from 4 hours of IHT or 2 hours of continuous hypoxia, but no response from 5 minutes or 1 hour. The IHT was a simulated altitude of 18,000 ft
* Subjects exposed hypoxia in a hypobaric chamber showed elevated EPO levels after 114 mins at 9,000 feet and or after 84 minutes at 12,000 feet. EPO levels continued to rise with longer exposure. <ref name="acu"/>
<ref name="USSR">http://www.ncbi.nlm.nih.gov/pubmed/12162864 Intermittent hypoxia research in the former soviet union and the commonwealth of independent States: history and review of the concept and selected applications.</ref>
<ref name="asthmatic">http://www.hypoxico.com/images/pdfs/Does_IHT_effect_the_lung_function_of_asthmatic_athletes.pdf Does IHT effect the lung function of asthmatic athletes</ref>
<ref name="junis">http://www.altitudecentre.com/images/Lincoln_Double_BlindIHT_Rep_2003.pdf Intermittent Hypoxic Training in Endurance Athletes</ref>
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