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* Expose subjects to 15,000 feet for 1 hour per day over several days for 7 to 11 sessions showed increased blood O2 O₂ saturation compared with initial exposure and the benefits were detectable for up to 4 weeks.* Exposure of 30 mins min to 3 hours every 2 to 3 days for 9 exposures increased hemoglobin by 12% and red blood cells by 22%* Exposure of 3x (6 min low O2, 4 min normal air) per day for 14 days increased breathing volume at altitude by ~50%. PO2 Partial pressure of O₂ started at 50 mmHg (20,000 ft) dropping to 35 mmHg (28,000 ft). Several studies have shown similar results. * 5x (15 min 11% O2 O₂ + 15 min recovery) for 14 day produced changes to the metabolic pathways that optimize the use of oxygen.

* A study of workers that cleaned up after Chernobyl nuclear reactor explosion showed that they had higher levels of oxidant stress where higher than normal. Exposing the workers to IHT of 3x (5 mins min 7-8% [28,000+ ft] O2 O₂ with 5 mins min normal air) for 14 days significantly reduced the oxidant stress.

* Research<ref name="jack"/> using highly trained runners showed no running improvement with IHT This research . However, this study used simulated altitudes IHT for 4 weeks and had O₂ saturation values of 1589.9,000 at the start rising to 2086.3, 85.9,000 feet at the endand 81.4 for each week. This gave O2 saturations The value of 90% at IHT is dependent upon the startO₂ saturation levels, going down to 80with little effect until values under 89% at <ref name="HTI"/>. The athletes in the endstudy therefore only received significant hypoxia for about one week. The athletes were given 5 mins min hypoxic, 5 mins nomal min normal for 70 minutes total for five days per week, 4 weeks total.

* Subjects exposed hypoxia in a hypobaric chamber showed elevated EPO levels after 114 mins min at 9,000 feet and or after 84 minutes at 12,000 feet. EPO levels continued to rise with longer exposure. <ref name="acu"/>* Research using the AltoLab system showed a significant improvement in sprint speed. The study used 6 mins min hypoxia (10,000 to 18,000 ft) with 4 min recovery for an hour a day for 15 days. The study shown a tiny improvement in blood parameters (hemoglobin/hematocrit) normally associated with altitude training.<ref name="alto"/>* IHT increased lung force in asthmatic and non-asthmatic athletes. There was no deterioration in asthma status from the trial, and half of the asthmatics reported a reduction in the need for medication. The trial used 15 sessions over three weeks, with each session being 5 mins min hypoxia followed by 5 mins min normal air, repeated for 60 minutes. The hypoxia was equivalent to 22,500 ft.<ref name="asthmatic"/> Other studies have reported a similar improvement in asthma, with reduced attacks, reduced severity of attacks and reduced need for medicatinmedication.