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From Fellrnr.com, Running tips
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If you get a blister, should you pop it? This is a question of finding the least bad option, as there is no ideal solution, other than preventing the blister in the first place ([[Blister Prevention]]).
The alternative to popping a blister due to pressure is to build up the area around the blister so that the pressure is relieved. Moleskin can be cut out in the shape of the blister, forming a doughnut shape that reduces pressure on the blister if it is small enough.
The best place for blister care supplies I found is [http://zombierunner.com" target="_blank zombierunner.comZombie Runner]. I would also recommend the book 'fixing your feet' by John Vonhof.