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MCT

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=Calories in MCT, Calorific Value and Weight Gain=An animal study has shown that overfeeding that includes large quantities of MCT produced 20% less weight gain than the same level of overfeeding with LCT<ref name="Geliebter-1983"/>. The rats were fed a diet of 50% of calories as fat, with the MCT diet providing 45% of calories from MCT. The rats had similar levels of activity and insulin. This may because MCTs are raise body temperature (thermogenesis)<ref name="Mascioli-1991"/>. MCT has is often considered to have a slightly lower calorie density of 8.3 Calories/gram compared with 9.1 Calories/gram for LCT<ref name="IngleDriedger1999"/>. However, if thermogenesis is taken into account, a value of 6.72 Calories/gram would be more appropriate<ref name="IngleDriedger1999"/>. This may be critical when using the [[MCT Diet]] if calorie intake is restricted. Given the density of MCT is 0.93 - 0.96 grams/ml<ref name="density"/>, 15ml of MCT would be 95 Calories assuming 6.72 Calories/gram rather than 118 Calories assuming 8.3 Calories/gram. =MCT and Weight Loss=MCTs are sometimes recommended for weight loss. One study compared MCTs with Olive Oil and found a greater weight loss with MCTs<ref name="St-Onge-2008"/>. There is some evidence from an animal study that MCTs may be less palatable than other fats<ref name="Edens-1984"/>. However, an analysis of animal studies indicates that generally, replacing other fats with MCT does not reduce calorie intake<ref name="Bach-1996"/>. Based on my personal experiences with MCT, I would suspect that any weight loss benefit comes from the appetite reduction that comes from the associated nausea.
=MCT Safety=
MCT is considered safe at 1mg/Kg of body weight, and MCT has been shown as effectively non-toxic in high dose animal studies<ref name="TraulDriedger2000"/>.
=My Experiences with MCT=
* I've found that taking MCT on its own will often produce digestive problems, including nausea and apocalyptic diarrhea. Mixing MCT with other foods can reduce the problems, and I'll take MCT with cream or other foods.
* I found that MCT in larger doses (3+ tablespoons) can produce obvious thermogenesis, resulting in the perception that a cold room is actually overly warm. There is also a sensation of warmth radiating from my stomach, rather like I'd just consumed strong alcohol.
* There seem to be changes in mental functioning, especially with larger doses. MCT can alleviate some feelings of tiredness and improve mental acuity, but it can also result in an unpleasant feeling that is hard to describe. The sensation is a little like how I feel when a migraine is imminent.
* I've found that MCT taken during exercise seems to impair my running. I performed a simplistic experiment with MCT during a run to try to evaluate the effect.
** At the time of the experiment I was adapted to the [[Ketogenic Diet], having blood ketones above 1.0 for the previous 10 days.
** I started the run fasted, with my last dose of MCT at 2 PM the previous day.
** For the first 8 miles, I felt really good, with my heart rate and breathing where I'd expect them to be.
** At 8 miles I took 3 tbsp. of MCT with 2 tbsp. of Nutella.
** By mile 10 my breathing had become strained, and I had to slow up slightly to keep things under control. My heart rate was slightly higher, but not enough to explain the breathlessness. My breathing problem peaked at about mile 11, before gradually easing off, though it never returned to normal.
** At mile 19 I stopped for a drink and my blood pressure dropped dramatically. Even crouched down with my head between my knees I was dizzy. After a few minutes things returned to some semblance of normality and I was eventually able to stand up and continued to run.
** A few days later I repeated the test, but took 3 tbsp. of Macadamia Nut Oil with 2 tbsp. of Nutella at mile 8. My breathing remained normal and I had no other problems.
=See Also=
{{KetoSeeAlso}}
=References=
<ref name="Mascioli-1991"> EA. Mascioli, S. Randall, KA. Porter, G. Kater, S. Lopes, VK. Babayan, GL. Blackburn, BR. Bistrian, Thermogenesis from intravenous medium-chain triglycerides., JPEN J Parenter Enteral Nutr, volume 15, issue 1, pages 27-31, PMID [http://www.ncbi.nlm.nih.gov/pubmed/1901104 1901104]</ref>
<ref name="IngleDriedger1999">D.L. Ingle, A. Driedger, K.A. Traul, D.K. Nakhasi, Dietary Energy Value of Medium-chain Triglycerides, Journal of Food Science, volume 64, issue 6, 1999, pages 960–963, ISSN [http://www.worldcat.org/issn/0022-1147 0022-1147], doi [http://dx.doi.org/10.1111/j.1365-2621.1999.tb12259.x 10.1111/j.1365-2621.1999.tb12259.x]</ref>
<ref name="St-Onge-2008">MP. St-Onge, A. Bosarge, Weight-loss diet that includes consumption of medium-chain triacylglycerol oil leads to a greater rate of weight and fat mass loss than does olive oil., Am J Clin Nutr, volume 87, issue 3, pages 621-6, Mar 2008, PMID [http://www.ncbi.nlm.nih.gov/pubmed/18326600 18326600]</ref>
<ref name="Edens-1984">NK. Edens, MI. Friedman, Response of normal and diabetic rats to increasing dietary medium-chain triglyceride content., J Nutr, volume 114, issue 3, pages 565-73, Mar 1984, PMID [http://www.ncbi.nlm.nih.gov/pubmed/6699737 6699737]</ref>
<ref name="Bach-1996">AC. Bach, Y. Ingenbleek, A. Frey, The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy?, J Lipid Res, volume 37, issue 4, pages 708-26, Apr 1996, PMID [http://www.ncbi.nlm.nih.gov/pubmed/8732772 8732772]</ref>
<ref name="Kossoff-2011-1809">Eric. Kossoff, [http://www.amazon.com/Ketogenic-Diets-Eric-H-Kossoff/dp/1936303108 Ketogenic diets : treatments for epilepsy and other disorders], date 2011, publisher Demos Health, location New York, isbn 1-936303-10-8, Kindle Offset 1809</ref>
</references>

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