SpO2

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SpO2 is the measure of the amount of oxygen in the blood. It stands for Saturation of peripheral Oxygen (O2) and is normally measured with a Pulse Oximeter.

1 Effects of hypoxia

Low levels of SpO2 effect brain functioning[1], as shown in the following table.

SpO2 Description Effect Notes
100-80% Mild Hypoxia Normal brain functioning This mild level of hypoxia does not affect the functioning of the brain, but some people can be sensitive enough to detect changes.
80-60% Moderate Hypoxia Decreasing brain function Vision can be altered, including tunnel vision. Coordination is impaired in things like handwriting will deteriorate. Below 80% the skin may become blue (cyanosis). Mental functioning is impaired, sometimes creating euphoria or tranquility, including indifference to everything including pain. At this level some people become fixated on whatever they were doing when the hypoxia began, which can be dangerous. Memory and speech can also be impaired. There may be older treat visual hallucinations, feelings of depersonalization and even out of body experiences.
60-40% Severe hypoxia Muscle paralysis Apparent unconsciousness.
<40% Extreme hypoxia Unconsciousness and eventually death


2 Hypoxia at altitude

The following table[2] gives an idea of different SpO2 levels at different altitudes. However, Intermittent Hypoxic Exposure can increase SpO2 levels at a given altitude[3], which are specified in the table below for some altitudes.

Altitude(feet) Altitude(meters) Air Pressure(mmHg) Oxygen Pressure(mmHg)  % of sea level Oxygen Equivalent O2 partial
pressure at sea level
SpO2
Unconditioned
SpO2
Conditioned
0 0 760 159 100 20.9 98%
5,000 1,524 639 134 84 17.6 95%
7,500 2,286 584 122 77 16.1 93%
9,000 2,740 554 116 73 15.3 90.3% (+/-3.4%) 93.8% (+/-2%)
10,000 3,048 534 112 70 14.6 89%
11,000 3,360 514 107 68 14.2 86.4 % (+/- 4.8%) 90.2% (+/-2.7%)
12,500 3,810 487 102 64 13.4 87%
14,000 4,267 460 96 61 12.7 83%
15,000 4,570 443 93 58 12.1 81.7% (+/-6%) 89.1% (+/-3%)
16,500 5,029 418 87 55 11.5 77%
18,000 5,490 395 83 52 10.9 84.9% (+/-4%)
20,000 6,096 365 76 48 10.0 65%
21,000 6,400 351 73 46 9.6 79.2% (+/-6%)
25,000 7,620 299 62 39 8.2 <60%

3 References

  1. anesthesia and hypoxia http://www.anesthesiaweb.org/hypoxia.php
  2. anesthesia and hypoxia http://www.anesthesiaweb.org/hypoxia.php Originally from "The Pilot: An Air Breathing Mammal," Mehler, Stanley R. MD, Human Factors Bulletin, Flight Safety Foundation, 1981.
  3. The Effect of Dynamic Intermittent Hypoxic Conditioning on Arterial Oxygen Saturation http://www.wemjournal.org/article/S1080-6032%2809%2970080-8/abstract