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From Fellrnr.com, Running tips
→NSAIDs and Racing
* It seems likely that NSAIDs will increase the risk of injury rather than reducing it, as the symptoms of damage will be masked.
* The most common NSAID for racing seems to be ibuprofen. I've not seen any evidence of the relative effectiveness of different NSAIDs on performance.
* It is better to take liquid ibuprofen than tablets or capsules. The tablets and capsules take longer to dissolve and if you have a digestive problem they may not be fully absorbed. You can chew the tablets, but this is unpleasant and ibuprofen can irritate your mouth and throat slightly, so the liquid form is best. It's obviously harder to transport, but you can fill an old film canister with a dose.
* Before an ultramarathon race, you should think through under what circumstances you will consider using NSAIDs and what dosage. Make sure your crew knows that you're taking NSAIDs in case anything happens.
* Extra care should be taken when NSAIDs are used in combination with dehydration, sickness or running the causes serious muscle damage.