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Created page with "Introduction/Summary.
{{Skeleton}}
=History=
* Medieval history
* Fasting in early 20<sup>th</sup> century
* Rise of the Ketogenic Diet
* Displacement with drug therapy
*..."
Introduction/Summary.
{{Skeleton}}
=History=
* Medieval history
* Fasting in early 20<sup>th</sup> century
* Rise of the [[Ketogenic Diet]]
* Displacement with drug therapy
* Resurgence and the Charlie foundation
=Evolution of the [[Ketogenic Diet]] for Epilepsy=
* Calorie restriction no longer used
* Fluid restriction no longer used
* New diets – [[MCT Diet]], [[Modified Atkins Diet]] MAD
* Wider usage
=General =
* The experts suggest that if the [[Ketogenic Diet]] is going to help with childhood seizures, it will do so within 3 months.
* The [[Ketogenic Diet]] has traditionally been fine tuned to maintain urine ketone levels to 3-4+ (80-160 mmol).
* Studies have shown a correlation between >90% seizure control and lower blood glucose levels.
* The availability of blood testing for [[Measuring Ketones]] is likely to improve our knowledge, as urine testing is rather limited.
* It is unclear if the [[Ketogenic Diet]] is safe for pregnancy in the general population, but it is probably much safer than anticonvulsant drugs that have known birth defect risks
* Taking a large drink can cause some (but not all) children to experience 'breakthrough seizures'<ref name="Kossoff-2011-2220"/>.
=Initiation and Fasting=
* Value of fasting
* Hospitalization requirements
=Success rate for Epilepsy=
* 50% of patients have a 50% reduction in seizures
* 25% have 90% reduction in seizures
* Around 10% become seizure free.
* The success rate also varies with the type of epilepsy
** chapter 5 ("Is my child a good candidate for the [[Ketogenic Diet]]") of "[http://www.amazon.com/Ketogenic-Diets-Eric-H-Kossoff/dp/1936303108 Ketogenic Diets: treatments for epilepsy and other disorders]" by Eric Kossoff for more details.
* In adults, weight loss is correlated with better response, though this could be due to the weight loss indicating better compliance with the diet.
=Types of Ketogenic Diets for Epilepsy=
There are several types of [[Ketogenic Diet]] used for epilepsy treatment:
* [[Ketogenic Ratio Diet]]. This diet has a strict controls over calorie intake and the ketogenic ratio, which is typically between 3:1 and 4:1. The diet is normally started with a hospital stay and includes a short fast.
* [[MCT Diet]]. This is a variant of the traditional diet that uses MCT oil that produces more ketones than other oils.
* [[Modified Adkins Diet]] (MAD). The MAD started by accident, when a child was put onto the Adkins diet prior to starting the traditional [[Ketogenic Diet]] and their seizures stopped.
* [[Low Glycemic Index Treatment]] (LGIT). The LGIT restricts the carbohydrate intake to only those foods with a [[Glycemic Index]] of less than 50. However, the LGIT is more than just restricting the glycemic index, and requires a fat intake of 60% with a ketogenic ratio of 1:1. The LGIT is similar to the MAD and restricts carbohydrates to 40-60 grams/day.
{{KetoSeeAlso}}
=References=
<references>
<ref name="Kossoff-2011-2220">Eric. Kossoff, [http://www.amazon.com/Ketogenic-Diets-Eric-H-Kossoff/dp/1936303108 Ketogenic diets : treatments for epilepsy and other disorders], date 2011, publisher Demos Health, location New York, isbn 1-936303-10-8, Kindle Offset 2220</ref>
</references>
{{Skeleton}}
=History=
* Medieval history
* Fasting in early 20<sup>th</sup> century
* Rise of the [[Ketogenic Diet]]
* Displacement with drug therapy
* Resurgence and the Charlie foundation
=Evolution of the [[Ketogenic Diet]] for Epilepsy=
* Calorie restriction no longer used
* Fluid restriction no longer used
* New diets – [[MCT Diet]], [[Modified Atkins Diet]] MAD
* Wider usage
=General =
* The experts suggest that if the [[Ketogenic Diet]] is going to help with childhood seizures, it will do so within 3 months.
* The [[Ketogenic Diet]] has traditionally been fine tuned to maintain urine ketone levels to 3-4+ (80-160 mmol).
* Studies have shown a correlation between >90% seizure control and lower blood glucose levels.
* The availability of blood testing for [[Measuring Ketones]] is likely to improve our knowledge, as urine testing is rather limited.
* It is unclear if the [[Ketogenic Diet]] is safe for pregnancy in the general population, but it is probably much safer than anticonvulsant drugs that have known birth defect risks
* Taking a large drink can cause some (but not all) children to experience 'breakthrough seizures'<ref name="Kossoff-2011-2220"/>.
=Initiation and Fasting=
* Value of fasting
* Hospitalization requirements
=Success rate for Epilepsy=
* 50% of patients have a 50% reduction in seizures
* 25% have 90% reduction in seizures
* Around 10% become seizure free.
* The success rate also varies with the type of epilepsy
** chapter 5 ("Is my child a good candidate for the [[Ketogenic Diet]]") of "[http://www.amazon.com/Ketogenic-Diets-Eric-H-Kossoff/dp/1936303108 Ketogenic Diets: treatments for epilepsy and other disorders]" by Eric Kossoff for more details.
* In adults, weight loss is correlated with better response, though this could be due to the weight loss indicating better compliance with the diet.
=Types of Ketogenic Diets for Epilepsy=
There are several types of [[Ketogenic Diet]] used for epilepsy treatment:
* [[Ketogenic Ratio Diet]]. This diet has a strict controls over calorie intake and the ketogenic ratio, which is typically between 3:1 and 4:1. The diet is normally started with a hospital stay and includes a short fast.
* [[MCT Diet]]. This is a variant of the traditional diet that uses MCT oil that produces more ketones than other oils.
* [[Modified Adkins Diet]] (MAD). The MAD started by accident, when a child was put onto the Adkins diet prior to starting the traditional [[Ketogenic Diet]] and their seizures stopped.
* [[Low Glycemic Index Treatment]] (LGIT). The LGIT restricts the carbohydrate intake to only those foods with a [[Glycemic Index]] of less than 50. However, the LGIT is more than just restricting the glycemic index, and requires a fat intake of 60% with a ketogenic ratio of 1:1. The LGIT is similar to the MAD and restricts carbohydrates to 40-60 grams/day.
{{KetoSeeAlso}}
=References=
<references>
<ref name="Kossoff-2011-2220">Eric. Kossoff, [http://www.amazon.com/Ketogenic-Diets-Eric-H-Kossoff/dp/1936303108 Ketogenic diets : treatments for epilepsy and other disorders], date 2011, publisher Demos Health, location New York, isbn 1-936303-10-8, Kindle Offset 2220</ref>
</references>