Changes

From Fellrnr.com, Running tips
Jump to: navigation, search

Ketogenic Diet as a Treatment

1,165 bytes added, 17:51, 15 August 2015
no edit summary
The [[Ketogenic Diet]] may have benefits for a number of medical conditions, many of them serious or life threatening. The research for the use of the Ketogenic Diet in epilepsy is well established, but for other illnesses it is still emerging. However, the Ketogenic Diet is believed to have a number of benefits, especially in cancer<ref name="Seyfried-2011"/> and neurological diseases like Alzheimer's and Parkinson's<ref name="Gasior-2006"/>. There are indications that the Ketogenic Diet might also help with Heart Disease, ALS, Autism, Hyperactivity, Schizophrenia, Depression and Bipolar disorder. However, these benefits must be balanced against the [[Health Risks of the Ketogenic Diet]].
=Epilepsy=
''Main article: [[Ketogenic Diets for Epilepsy]]''
* '''Head trauma'''. Head trauma often results in a rapid increase in cerebral glucose metabolism, followed by a prolonged decrease. Administering glucose to patients tends to result in hyperglycemia (high blood sugar) that worsens the outcome. In animal studies, fasting or a ketogenic diet improves tissue preservation, but further research is needed<ref name="Prins2007"/>.
* '''Stroke'''. Because a stroke involves the reduction of blood flow to areas of the brain, the Ketogenic diet may help reduce the resulting damage<ref name="GibsonMurphy2012"/>. Animal studies have looked at the ketogenic diet, ketone administration, and calorie restriction, which all raise ketone levels, and all have shown to be beneficial in animal stroke models<ref name="GibsonMurphy2012"/>.
[[File:Stroke outcome in the ketogenic state.png|none|thumb|500px|The analysis of 19 animal (rodent) studies on the changes in outcome following cerebral ischemia with the ketogenic state. Pathological outcomes included lesion volume, brain water content, and neuronal counts, whereas functional outcomes included all measures of behavior.]]
* '''Altitude Sickness'''. It is possible that the ketogenic diet may help with altitude sickness (Acute Mountain Sickness), but I've found not studies to support this.
=Heart disease=
=Depression and bipolar disorder=
There are a number of cases that have been reported where the ketogenic diet helps normalize the [[Mood State]] of those with bipolar disorder<ref name="El-MallakhPaskitti2001"/>. One report indicated that over 2-3 years the mood stabilization exceeded that achieved with medication<ref name="Phelps-2013"/>.
=Obesity=
A recent analysis of 13 trials comparing the Ketogenic Diet (KD) with a Low Fat Diet (LFD) showed that the KD resulted in greater weight loss (an extra 0.9Kg/2 pounds), reduced triglycerides and blood pressure, but increased cholesterol<ref name="Bueno-2013"/>. However, while the extra weight loss was statistically significant, the loss of an additional 0.9Kg/2 pounds has limited real world value when the [[Health Risks of the Ketogenic Diet]] are considered<ref name="Bueno-2013"/>.
=See Also=
{{KetoList}}
=References=
<references>
<ref name="Bueno-2013">NB. Bueno, IS. de Melo, SL. de Oliveira, T. da Rocha Ataide, Very-low-carbohydrate ketogenic diet v. low-fat diet for long-term weight loss: a meta-analysis of randomised controlled trials., Br J Nutr, volume 110, issue 7, pages 1178-87, Oct 2013, doi [http://dx.doi.org/10.1017/S0007114513000548 10.1017/S0007114513000548], PMID [http://www.ncbi.nlm.nih.gov/pubmed/23651522 23651522]</ref>
<ref name="El-MallakhPaskitti2001">R.S. El-Mallakh, M.E. Paskitti, The ketogenic diet may have mood-stabilizing properties, Medical Hypotheses, volume 57, issue 6, 2001, pages 724–726, ISSN [http://www.worldcat.org/issn/03069877 03069877], doi [http://dx.doi.org/10.1054/mehy.2001.1446 10.1054/mehy.2001.1446]</ref>
<ref name="Phelps-2013"> JR. Phelps, SV. Siemers, RS. El-Mallakh, The ketogenic diet for type II bipolar disorder., Neurocase, volume 19, issue 5, pages 423-6, 2013, doi [http://dx.doi.org/10.1080/13554794.2012.690421 10.1080/13554794.2012.690421], PMID [http://www.ncbi.nlm.nih.gov/pubmed/23030231 23030231]</ref>

Navigation menu