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Other factors to consider
* Running is a higher intensity exercise than cycling for most people. The higher intensity tends to help with weight loss by improving the muscle's sensitivity to insulin. Though higher intensity tends to burn less fat during the exercise, the actual amount of fat burned is relatively small for many athletes and appetite tends to rise to compensate. The improved sensitivity to insulin appears to be the major source of weight loss from exercise.
* Running tends to be better for weight loss given an equivalent energy expenditure<ref name="Williams-2012"/>.
* Running uses more muscles than seated cycling, which leads to improved insulin sensitivity across those muscles.
* Because running is load bearing exercise, it tends to improve bone strength. However, this also means that running must be started carefully to prevent overload and injury.
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=References=
<references>
<ref name="Williams-2012">{{Cite journal | last1 = Williams | first1 = PT. | title = Non-Exchangeability of Running vs. Other Exercise in Their Association with Adiposity, and Its Implications for Public Health Recommendations. | journal = PLoS One | volume = 7 | issue = 7 | pages = e36360 | month = | year = 2012 | doi = 10.1371/journal.pone.0036360 | PMID = 22808000 }}</ref>
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