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The Science of Intermittent Hypoxic Exposure

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* Subjects exposed hypoxia in a hypobaric chamber showed elevated EPO levels after 114 min at 9,000 feet and or after 84 minutes at 12,000 feet. EPO levels continued to rise with longer exposure. <ref name="acu"/>
* Research using the [[AltoLab]] system showed a significant improvement in sprint speed. The study used 6 min hypoxia (10,000 to 18,000 ft) with 4 min recovery for an hour a day for 15 days. The study shown a tiny improvement in blood parameters (hemoglobin/hematocrit) normally associated with altitude training.<ref name="alto"/>
* IHE and asthma** IHE increased lung force in asthmatic and non-asthmatic athletes<ref name="asthmatic"/>. There was no deterioration in asthma status from the trial, and half of the asthmatics reported a reduction in the need for medication. The trial used 15 sessions over three weeks, with each session being 5 min hypoxia followed by 5 min normal air, repeated for 60 minutes. The hypoxia was equivalent to 22,500 ft.** IHE has been shown to reduce the shortness of breath and congestion of childhood bronchial asthma, reducing or eliminating the attacks<ref name="asthmaticSerebrovskaya-2012"/> . The protocol was 4 repeats of 5-7 minutes with 12% O<sub>2</sub> which resulted in a [[SpO2|SpO<sub>2</sub>]] of 89-92%. Other studies have reported a similar improvement in asthma, with reduced attacks, reduced severity of attacks and reduced need for medication.
==IHE and Live High, Train Low==
<ref name="junis">http://www.altitudecentre.com/images/Lincoln_Double_BlindIHE_Rep_2003.pdf Intermittent Hypoxic Training in Endurance Athletes</ref>
<ref name="HTI">http://en.wikipedia.org/wiki/Hypoxic_Training_Index Hypoxic Training Index</ref>
<ref name="Serebrovskaya-2012">Serebrovskaya, Tatiana V., et al. "Intermittent Hypoxia in Treatment of Bronchial Asthma in Childhood." Intermittent Hypoxia and Human Diseases. Springer London, 2012. 135-143.</ref>
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